Genome-wide identification and functional prediction of novel and drought-responsive lincRNAs in Populus trichocarpa

نویسندگان

  • Peng Shuai
  • Dan Liang
  • Sha Tang
  • Zhoujia Zhang
  • Chu-Yu Ye
  • Yanyan Su
  • Xinli Xia
  • Weilun Yin
چکیده

Protein-coding genes are considered to be a dominant component of the eukaryotic transcriptome; however, many studies have shown that intergenic, non-coding transcripts also play an important role. Long intergenic non-coding RNAs (lincRNAs) were found to play a vital role in human and Arabidopsis. However, lincRNAs and their regulatory roles remain poorly characterized in woody plants, especially Populus trichocarpa (P. trichocarpa). A large set of Populus RNA-Seq data were examined with high sequencing depth under control and drought conditions and a total of 2542 lincRNA candidates were identified. In total, 51 lincRNAs and 20 lincRNAs were identified as putative targets and target mimics of known Populus miRNAs, respectively. A total of 504 lincRNAs were found to be drought responsive, eight of which were confirmed by RT-qPCR. These findings provide a comprehensive view of Populus lincRNAs, which will enable in-depth functional analysis.

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عنوان ژورنال:

دوره 65  شماره 

صفحات  -

تاریخ انتشار 2014